Overview of Briganix 90mg Tablets

Composition: Contains Brigatinib 90mg.
– Substitutes: Trepmac, Alunbrig.
– Shipping Class: Room Temperature.

Uses

– Primary Use: Treats a specific type of lung cancer known as non-small cell lung cancer (NSCLC) by inhibiting the growth of cancer cells.

Side Effects

–Common Side Effects: May include nausea, vomiting, diarrhea, loss of appetite, abdominal pain, constipation, fatigue, dizziness, fever, headaches, insomnia, or joint pain. If these persist or worsen, contact a healthcare professional.

How to Use

-Administration Instructions: Take orally with or without food as prescribed by a healthcare provider. Swallow tablets whole without crushing or chewing.

Mechanism of Action

–Function: Acts as an anaplastic lymphoma kinase (ALK) inhibitor, demonstrating significant effectiveness in treating ALK-positive NSCLC.

Important Information

– Monitoring for Pulmonary Reactions: Watch for symptoms of interstitial lung disease/pneumonitis, especially within the first week of treatment.
– Blood Pressure Management: Manage blood pressure before starting treatment; monitor after two weeks and monthly thereafter.
– Heart Rate Monitoring: Be aware of potential bradycardia; monitor heart rate and blood pressure regularly.
– Visual Disturbances: Report any changes in vision.
– Muscle Health: Increased creatine phosphokinase (CPK) levels can occur; report unexplained muscle symptoms and monitor CPK levels.
– Pancreatic Enzymes: Monitor lipase and amylase levels due to potential increases.
– Blood Sugar Levels: Assess and monitor fasting serum glucose; adjust antihyperglycemic medications as needed.

Warnings and Precautions

– Alcohol: May exacerbate dizziness or vision issues; limit alcohol consumption.
– Pregnancy: Potential to harm the fetus; evaluate risks and benefits.
– Lactation: Not recommended due to potential risk to the infant; consult a doctor before breastfeeding.
– Driving: Exercise caution due to possible dizziness or vision blur.
– Kidney Function: Use cautiously in patients with kidney disease; monitor kidney function closely.
– Liver Function: Use cautiously in patients with liver disease; monitor liver function closely.

Missed Dose Guidance

– If a dose is missed, skip it and continue with the next dose at the regular schedule. Do not double the dose.