Crizotinib is a targeted medicine used to treat particular forms of lung cancer. Xalkori is the brand name under which it is offered. It functions by preventing aberrant proteins that encourage the proliferation of cancer cells and is categorized as a tyrosine kinase inhibitor (TKI). Non-small cell lung cancer (NSCLC) that tests positive for ROS1 gene rearrangements or ALK (anaplastic lymphoma kinase) is the main condition for which xalkori is utilized.

Uses

Crizotinib is prescribed for:

Non-small cell lung cancer (NSCLC): in patients with cancers that have mutations in the ROS1 or ALK genes. ALK-positive anaplastic large cell lymphoma (ALCL) can occur in some individuals, especially in children and young adults. Additional Investigative Uses: It is being researched for possible application in other malignancies caused by comparable genetic abnormalities. Patients lacking ALK or ROS1 mutations should not use this medication. Before Xalkori is prescribed, genetic testing is necessary.

Dosage and Administration

Suggested Dosage: Adults should take 250 mg orally twice a day, with or without food. missing Dose: Unless it is almost time for the next scheduled dose, take the missing dose as soon as you can. Avoid taking two doses at once. Overdose: Get medical help right away if you think you may have overdosed. Severe nausea, vomiting, or lightheadedness are all possible overdose symptoms. Dosage Adjustments: The doctor may lower the dosage in response to side effects, liver or renal function, or concurrent use of other drugs.

Side Effects

Typical adverse effects are typically mild to severe.
vomiting and nausea
Either constipation or diarrhea

Weakness and exhaustion
Issues with vision (double vision, hazy eyesight)
Hand, foot, or leg swelling
Headache and lightheadedness
Diminished appetite
Serious Side Effects (Need to see a doctor right away)
Liver issues: Dark urine, extreme nausea, and yellowing of the skin and eyes
Heart problems: Chest pain, dizziness, and a slow heartbeat
Lung issues include continuous coughing and shortness of breath.
Serious digestive problems: Prolonged diarrhea or excruciating stomach ache
Allergic reactions: breathing difficulties, puffiness, and rash
If any adverse effects worsen or continue, let your doctor know.

Storage Instructions

Keep in a dry location at ambient temperature (20°C to 25°C). Keep out of direct sunlight and moisture in the original container. Avoid keeping items in damp areas like the bathroom. Keep out of children’s and pets’ reach. Observe local disposal laws before discarding any unused medications.

Crizotinib (Xalkori) 250 mg Capsule Description
Look: A pink-capped white capsule
The formulation is an oral capsule with the labels “Pfizer” and “CRZ 250” on one side.
Packaging: Typically, bottles or blister packs are offered.

Conclusion

Now, crizotinib (Xalkori), a novel targeted drug, can be used to treat ALK/ROS1-positive lung cancer. Despite its effectiveness, there may be negative side effects that require medical supervision. Always take it as prescribed, store it as prescribed, and talk to a healthcare professional about any worries you may have.

Order Now At Mdx Pharma bd….

To order from MDX Pharma BD, visit their website at https://mdxpharmabd.com, where you can browse products and place orders online. For inquiries or orders via email, contact emedicarepharma@gmail.com. Alternatively, call (+88) 01929123476. Their address is 29, Abdullahpur, Uttara, Dhaka-1230, Bangladesh.

Q. Is chemotherapy inferior to crizotinib?
Crisotinib treatment led to a significantly longer progression-free survival, significantly greater response rates, a considerable decrease in symptoms, and a significant improvement in overall quality of life when compared to normal second-line chemotherapy.

Q. What is the most often used medication for chemotherapy?
Alkylating agents are the most often prescribed chemotherapeutic drugs. Additionally, they were the first class of chemotherapeutic medications created. However, depending on the type of cancer and its stage, alternative chemotherapy medications or drug combinations might be more prevalent.