Alexinib, a targeted cancer medication, is classified as an anaplastic lymphoma kinase (ALK) inhibitor. It is commonly used to treat ALK-positive non-small cell lung cancer (NSCLC). The medication comes in hard capsule form and contains 150 mg of alexinib, the active component. Usually white to off-white in hue, it is encased in a gelatin shell.

Uses

Alectinib is prescribed for patients with:

ALK-positive metastatic non-small cell lung cancer (NSCLC). ALK inhibitors can be used as a second-line treatment following Crizotinib failure or in patients who have never taken them before. It slows or stops the growth of tumors by blocking the ALK proteins that promote the proliferation of cancer cells.

Dosage and Administration

It is advised to take 600 mg (four 150 mg capsules) twice a day, for a daily total of 1,200 mg.
To enhance absorption, it should be taken with food.
Do not chew, crush, or open the capsule; instead, swallow it whole.

Take the missing dose as soon as you can, unless it’s almost time for the next one.
Do not take an additional dose if vomiting happens after taking one. Proceed with the subsequent dose as planned.

Side Effects

Alectinib may cause mild to severe side effects, including:

Fatigue
Nausea
Constipation
Muscle pain (myalgia)
Swelling in the hands, feet, or face

Serious side effects

Liver issues (dark urine, nausea, and skin/eye yellowing). Pneumonitis-related lung inflammation (shortness of breath, chronic cough, chest pain). Heart rate slowness (bradycardia). severe rhabdomyolysis, or injury to the muscles (pain in the muscles, black urine). Kidney issues (edema, altered urination). Sun sensitivity: Alectinib makes people more vulnerable to sunshine, which can result in serious sunburns. Patients should wear sunscreen with an SPF of 50+ and avoid prolonged sun exposure.

Precautions

Due to the possibility of injury to the unborn child, it is not advised for women who are pregnant or nursing. Tests for liver function should be routinely observed. Bradycardia is something that patients with heart issues should be watched for. Steer clear of grapefruit and grapefruit juice since they can affect how drugs are metabolized.

Storage

Alectinib should be kept between 20°C and 25°C (68°F and 77°F) at room temperature.
To keep the capsules safe from light and moisture, keep them in their original container.
Keep out of children’s and pets’ reach. Avoid using medication that has expired and dispose of unused capsules in accordance with local laws.

Conclusion

Alexinib 150 mg is an effective drug that reduces the growth of ALK-positive non-small cell lung cancer. However, it could have serious side effects that necessitate constant medical monitoring. Always report any strange symptoms and do as your doctor instructs.

Order Now At Mdx Pharma bd….

To order from MDX Pharma BD, visit their website at https://mdxpharmabd.com, where you can browse products and place orders online. For inquiries or orders via email, contact emedicarepharma@gmail.com. Alternatively, call (+88) 01929123476. Their address is 29, Abdullahpur, Uttara, Dhaka-1230, Bangladesh.

Q. What kind of cancer is treated with alectinib?

Alecensa is another name for it. Alectinib is pronounced al-ek-ti-nib. It is a treatment for spread-resistant non-small cell lung cancer (NSCLC). If there is a mutation in the anaplastic lymphoma kinase (ALK) gene in your malignancy, you are on alectinib.

Q. What is the new lung cancer medication?

The first KRAS-targeting medication for non-small cell lung cancer was approved by 2021. Adult patients with a certain mutation known as KRAS G12C can use this medication, sotorasib (LumakrasTM). Recently, adagrasib (Krazati®), another medication, was authorized to treat certain mutations.