CERINIB 150 mg is a prescription drug that is mainly used to treat non-small cell lung cancer (NSCLC), a particular kind of lung cancer. It is sold under the brand name Zykadia. Patients with malignancies that are anaplastic lymphoma kinase (ALK)-positive—that is, where the cancer cells have a mutant ALK gene that propels their growth—are especially recommended to use it. Zykadia is a targeted oral medication that slows or stops the growth of cancer cells by blocking the action of the ALK protein.

Ceritinib, a selective ALK inhibitor, is the active component of CERINIB. Ceritinib is a member of the tyrosine kinase inhibitor (TKI) medication class. By targeting ALK and other related kinases, ceritinib helps block the signaling pathways that cancer cells rely on for survival and proliferation.

The dosage of ceritinib, which is 150 mg per tablet, is often determined by the patient’s tolerance, reaction to treatment, and overall health. In order to reduce gastrointestinal side effects, patients usually take several tablets daily as directed by their oncologist, frequently without meals.

Patients who have been resistant or intolerant to a prior ALK inhibitor, like crizotinib, benefit most from INIB (Zykadia). It is also a good choice for people whose cancer has progressed to the brain because of its capacity to pass the blood-brain barrier.

How It Works

Cerinib 150 mg (Zykadia) stops cancer cells from proliferating and encourages cancer cell death by blocking the aberrant ALK protein signals in cancer cells. Compared to conventional chemotherapy, which targets both healthy and malignant cells equally, this focused method frequently produces greater results and fewer adverse effects.

Common Side Effects

Like all medications, CERINIB may cause side effects. Some common ones include:

• Nausea
• Diarrhea
• Vomiting
• Abdominal pain
• Fatigue
• Increased liver enzymes
• Loss of appetite
• Constipation

Additionally, there is a chance of serious side effects include hyperglycemia, lung inflammation, and cardiac rhythm issues like QT prolongation. Throughout therapy, routine monitoring by a healthcare professional is crucial to quickly managing any side effects.

Precautions

Prior to beginning CERINIB medication, patients should let their doctor know about:

Any gastrointestinal, cardiac, or hepatic disorders that may be present

Supplements or other drugs they are taking

Status of pregnancy or nursing

Effective contraception should be used during therapy and for a period following the last dose due to possible dangers to the fetus.

Storage and Handling

CERINIB should be kept out of the heat and moisture and at room temperature. It should not be used after the expiration date indicated on the container and must be kept out of children’s reach.

Order Now At Mdx Pharma bd….

To order from MDX Pharma BD, visit their website at https://mdxpharmabd.com, where you can browse products and place orders online. For inquiries or orders via email, contact emedicarepharma@gmail.com. Alternatively, call (+88) 01929123476. Their address is 29, Abdullahpur, Uttara, Dhaka-1230, Bangladesh.

1. What is the purpose of 150 mg of Ceritinib?
Patients with metastatic (cancer that has spread) non-small cell lung cancer who have a particular kind of aberrant anaplastic lymphoma kinase (ALK) gene are treated with ceritanib. The presence of this gene will be tested for by your physician. Ceritinib is a substance that fights cancer.

2. What is Zykadia’s brand name?
Zykadia’s Ceritinib One kind of targeted medication is ceretinib. Another name for it is Zykadia. It is a treatment for non-small cell lung cancer, which is characterized by the presence of the enzyme anaplastic lymphoma kinase (ALK).

3. What is the indication for ceritinib?
Patients with anaplastic lymphoma kinase (ALK)-positive metastatic non-small cell lung cancer (NSCLC) who have progressed on crizotinib or who are intolerant to it can be treated with crizitinib, a kinase inhibitor.

4. Ceritinib belongs to which generation?
Currently, crizotinib, a first-generation ALK inhibitor, is used to treat advanced, anaplastic lymphoma kinase (ALK)-positive lung cancer. As the disease progresses, more powerful second-generation ALK inhibitors, such as ceritinib and alectinib, are used.

5. Which business produced ceritinib?
Novartis 150 mg capsules of Ceritinib. A specific kind of non-small cell lung cancer (NSCLC) that has metastasized to other body areas is treated with ceritanib.