Pazopanib 200 mg (Votrient) is an oral medication used for the treatment of certain types of cancer, including renal cell carcinoma (RCC) and soft tissue sarcoma (STS). It is marketed under the brand name Votrient and is a tyrosine kinase inhibitor (TKI) that works by blocking the activity of several proteins involved in cancer cell growth and the formation of blood vessels (angiogenesis).

Pazopanib 200 mg (Votrient)

Product Overview: Pazopanib 200 mg (Votrient) is a tyrosine kinase inhibitor (TKI) used to treat renal cell carcinoma (RCC) and soft tissue sarcoma (STS). Votrient works by inhibiting multiple receptors involved in the growth of cancer cells and the formation of new blood vessels that tumors need to grow. By blocking these pathways, Pazopanib helps slow or stop the progression of cancer, improving patient outcomes.

Key Benefits:

• Effective treatment for advanced renal cell carcinoma (RCC) and soft tissue sarcoma (STS).
• Inhibits angiogenesis (formation of new blood vessels) to starve tumors and prevent their growth.
• Oral administration provides convenience for patients.

Indications:

• Renal cell carcinoma (RCC): Pazopanib is indicated for the treatment of advanced renal cell carcinoma, either as a first-line treatment or for patients who have received prior therapy.
• Soft tissue sarcoma (STS): Approved for the treatment of soft tissue sarcoma in patients who have received prior chemotherapy.

Dosage:

• The usual dose is 200 mg once daily, taken orally, with or without food.
• Dosage adjustments may be required based on side effects, liver function, or patient tolerance.
• Do not take more than the prescribed dose. If you miss a dose, take it as soon as you remember, unless it’s almost time for your next dose. In that case, skip the missed dose and continue with your regular schedule.

Precautions:

• Pazopanib may cause liver toxicity; therefore, regular liver function tests should be done.
• Monitor for signs of high blood pressure, heart problems, or gastrointestinal perforations, which can be serious side effects.
• Not recommended during pregnancy or breastfeeding.
• Blood pressure and heart function should be regularly checked during treatment, as Pazopanib can cause elevated blood pressure and heart issues.

Common Side Effects:

• Fatigue
• Diarrhea
• High blood pressure
• Nausea and vomiting
• Loss of appetite
• Liver enzyme elevations
• Hair color change
• Skin reactions (e.g., hand-foot syndrome)

Packaging:

• Pazopanib 200 mg (Votrient) tablets are packaged in a [insert packaging type] for safe and convenient administration.

Important Notes:

• Pazopanib is a prescription medication and should be used under the supervision of a healthcare provider.
• Regular monitoring of liver function, blood pressure, and heart health is required while on treatment.
• Store the medication in a cool, dry place, away from sunlight and moisture. Keep it out of reach of children.