Indication:
PAZONIB-200 (Pazopanib) 200mg is used to treat advanced renal cell carcinoma (RCC) and soft tissue sarcoma.

Pharmacology:
Pazopanib inhibits multiple receptors involved in tumor angiogenesis and cell proliferation, thereby halting tumor growth and spread.

Dosage and Administration:
The standard dose is one 200mg tablet taken orally once daily, preferably on an empty stomach.

Interactions:
PAZONIB-200 may interact with various medications, including other anti-cancer drugs and certain antibiotics. Patients should inform their healthcare provider about all medications they are taking.

Side Effects:
Common side effects include high blood pressure, fatigue, diarrhea, nausea, vomiting, decreased appetite, and abnormal liver function tests. Serious side effects such as liver problems, bleeding, and cardiovascular events are also possible.

Precautions and Warnings:
Patients with hypertension should have their blood pressure controlled before starting treatment. Regular monitoring of blood pressure, liver function, and thyroid function is necessary. Caution is advised in patients with a history of cardiovascular disease or gastrointestinal disorders, and pregnant or breastfeeding women should avoid the medication.

Overdose Effects:
Overdose may lead to worsening side effects, including severe hypertension, gastrointestinal issues, and liver problems. Management involves supportive care and close monitoring of vital signs.