Obeticholic Acid 5 mg (Ocaliva) is a medication used for the treatment of primary biliary cholangitis (PBC), a chronic liver disease that occurs when the bile ducts in the liver become damaged and blocked. It is marketed under the brand name Ocaliva and is a farnesoid X receptor (FXR) agonist, which helps improve bile flow and reduces liver inflammation.

Obeticholic Acid 5 mg (Ocaliva)

Product Overview: Obeticholic Acid 5 mg (Ocaliva) is an oral medication used for the treatment of primary biliary cholangitis (PBC), a progressive liver disease. Ocaliva works by activating the farnesoid X receptor (FXR), which plays a crucial role in bile acid regulation and liver health. By modulating bile acid production and improving bile flow, Obeticholic Acid helps reduce liver damage and inflammation in patients with PBC.

Key Benefits:

• Effective treatment for primary biliary cholangitis (PBC), reducing liver inflammation and improving liver function.
• Oral medication, offering convenience and easier administration compared to other treatments.
• Helps slow disease progression and improve the quality of life in patients with PBC.

Indications:

• Primary biliary cholangitis (PBC), either alone or in combination with ursodeoxycholic acid (UDCA) for patients who do not respond adequately to UDCA therapy.

Dosage:

• 5 mg once daily for patients new to Ocaliva. The dose may be adjusted based on individual patient response and tolerability.
• In some patients, the dose may be increased to 10 mg once daily after an initial treatment period.
• Obeticholic Acid should be taken orally with or without food. Your healthcare provider will determine the correct dosage based on your condition and response to treatment.

Precautions:

• Liver function monitoring: Obeticholic Acid can cause liver-related side effects, so regular liver function tests are required during treatment.
• Risk of itching (pruritus): One of the common side effects of Ocaliva is itching, which should be monitored and managed.
• Pregnancy and breastfeeding: Ocaliva is not recommended during pregnancy or while breastfeeding unless the benefits outweigh the risks.
• Not recommended for use in patients with cirrhosis or advanced liver disease that is not associated with PBC.

Common Side Effects:

• Itching (pruritus)
• Fatigue
• Jaundice (yellowing of the skin or eyes)
• Elevated liver enzymes
• Abdominal pain
• Headache

Packaging:

• Obeticholic Acid 5 mg (Ocaliva) tablets are packaged in [insert packaging type] for easy administration.

Important Notes:

• Always follow your healthcare provider’s instructions for the correct dosage and frequency.
• Regular monitoring of liver function and assessment of side effects is necessary during treatment.
• Store in a cool, dry place, away from direct sunlight, and keep out of reach of children.