Eltrombopag 50 mg (Olamine)

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Elbonix is a tablet form of a small-molecule TPO-receptor agonist that can be taken orally. It interacts with the transmembrane domain of the human TPO-receptor, prompting signaling pathways that stimulate both proliferation and differentiation from bone marrow progenitor cells.

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    Eltrombopag Olamine, the active ingredient in Eltrombopag 50 mg, is an oral drug that stimulates platelet formation to treat specific blood diseases. It is mostly prescribed for patients with severe aplastic anemia, chronic hepatitis C-associated thrombocytopenia, and chronic immune thrombocytopenia (ITP). It is a member of the class of medications known as thrombopoietin receptor agonists.

     

    Eltrombopag 50 mg, which is produced in accordance with stringent pharmaceutical standards, is a useful therapeutic choice intended to raise platelet counts in patients whose platelet counts are dangerously low, lowering the risk of severe bleeding episodes.


    Composition:

    Ingredient in Action: Eltrombopag Olamine

     

    50 milligrams of strength

     

    Form: tablet with a film coating

     

    Packaging: blister pack; depending on the prescription, there are typically seven or twenty-eight tablets each pack.


    Mechanism of Action:

    Eltrombopag 50 mg Olamine) functions by attaching itself to bone marrow precursor cells and activating the thrombopoietin (TPO) receptor. Platelet production rises as a result of this activation, which also promotes megakaryocyte differentiation and production. Eltrombopag 50 mg encourages endogenous platelet synthesis from within the body, providing a more long-lasting therapy alternative for chronic diseases than standard platelet transfusions.


    Indications:

    The following illnesses are treated with 50 mg of Eltrombopag 50 mg:

     

    Patients aged one year and up who have not reacted well to corticosteroids, immunoglobulins, or splenectomy are treated with chronic immune thrombocytopenia (ITP).

     

    In individuals with low platelet counts who have chronic hepatitis C, thrombocytopenia is indicated to enable the start and continuation of interferon-based therapy.

     

    Patients with severe aplastic anemia who have not responded adequately to immunosuppressive treatment are treated with this medication.


    Dosage & Administration:

    Adults usually begin taking 50 mg once daily, with or without food.

    Depending on the patient’s platelet count and reaction to treatment, the dosage may be changed.

    A lower initial dose (25 mg once daily) might be advised for people with hepatic impairment or those of East Asian heritage.

    Dairy products, drinks enriched with calcium, and antacids that contain aluminum, calcium, or magnesium should not be used with Eltrombopag 50 mg since they may hinder the absorption of the medication.

    Throughout the duration of treatment, routine monitoring of liver function and platelet counts is crucial.

    Note: Before altering the dosage, always get advice from a healthcare professional and follow your doctor’s instructions.


    Side Effects:

    Side effects are possible with Eltrombopag 50 mg, just like with other drug. Among the most typical are:

     

    A headache

     

    Feeling queasy

     

    Weariness

     

    Having diarrhea

     

    Pain in the muscles

     

    infections of the upper respiratory tract

     

    The following are serious but uncommon adverse effects:

     

    Abnormalities of liver enzymes

     

    Formation of cataracts

     

    A higher chance of blood clots

     

    Fibrosis of the bone marrow (rare)

     

    Patients should notify their healthcare practitioner right once if they experience any jaundice, changes in eyesight, or symptoms of thrombosis, such as chest pain or limb swelling.


    Contraindications & Precautions:

    Patients who have a history of known hypersensitivity to Eltrombopag or any of its ingredients should not take Eltrombopag 50 mg. One should exercise caution:

     

    Individuals who have experienced thromboembolic episodes in the past

     

    Hepatic impairment patients

     

    Women who are pregnant or nursing (only if medically recommended and plainly needed)

     

    Youngsters under one year old (unless otherwise noted)


    Drug Interactions:

    Eltrombopag 50 mg may interact with a number of other drugs and medications:

     

    Antacids, iron, calcium, magnesium, and supplements containing aluminum should not be taken together since this may decrease the drug’s absorption.

     

    Drug interactions that impact the CYP1A2 and UGT1A1 enzymes need to be closely watched.

     

    Steer clear of grapefruit juice as it may disrupt the liver enzymes that are involved in the metabolism of drugs.


    Storage:

    Store in a dry location below 30°C (86°F).

     

    Steer clear of wetness and direct sunshine.

     

    Keep out of children’s reach.


    Conclusion:

    In a variety of medical situations, Eltrombopag 50 mg is a useful therapeutic choice for thrombocytopenia. It gives patients an opportunity to lower their risk of bleeding and enhance their quality of life by promoting the body’s natural synthesis of platelets, particularly in cases where traditional treatments have not worked. Like any drug, it should only be taken under the direction and care of a licensed healthcare provider. To guarantee the best results, it should be monitored frequently.


    Order Now At Mdx Pharma bd….

    To order from MDX Pharma BD, visit their website at https://mdxpharmabd.com, where you can browse products and place orders online. For inquiries or orders via email, contact emedicarepharma@gmail.com. Alternatively, call (+88) 01929123476. Their address is 29, Abdullahpur, Uttara, Dhaka-1230, Bangladesh.

     

    1. What is the purpose of the Eltrombopag 50 mg Tablet?
    Eltrombopag Tablet 50 mg is used to treat low platelet counts brought on either a chronic hepatitis C virus (HCV) infection or chronic immunological (idiopathic) thrombocytopenic purpura (ITP). Additionally, severe aplastic anemia is treated with it.

     

    2. What is the purpose of 50 mg of Eltrombopag?
    Eltrombopag is used to treat people with chronic immune thrombocytopenia (ITP), a blood condition characterized by insufficient platelets in the blood. After a splenectomy (splenic removal operation) and other medications (such as immunoglobulin or steroids) have not been effective enough, this medication is taken.

     

    3. Is eltrombopag a medication used in chemotherapy?
    Eltrombopag is licensed by the US Food and Drug Administration (FDA) to treat low platelet disorders such as chronic immune thrombocytopenia (ITP) that are not connected to chemotherapy.

     

    4. What time of day is ideal for taking eltrombopag?
    Typically, it is taken once daily on an empty stomach, either two hours after eating or at least one hour before. Every day, take eltrombopag at roughly the same time. Pay close attention to the instructions on your prescription label, and ask your pharmacist or doctor to clarify any parts you don’t understand.