Doxofylline is the active ingredient of the pharmaceutical drug. It is mainly used to treat respiratory disorders marked by airway obstruction and bronchospasm, such as asthma and chronic obstructive pulmonary disease (COPD). It is a member of the methylxanthines pharmacological class. facilitates better breathing by relaxing the airway muscles and increasing lung airflow.

Active Ingredient

• Doxofylline – 200 mg

Although it shares structural similarities with theophylline, doxofylline is a xanthine derivative that has a superior safety record and fewer adverse effects. It reduces inflammation in the airways and causes bronchodilation by blocking the phosphodiesterase enzyme.

Mechanism of Action

By relaxing the bronchial tubes’ smooth muscles, doxofylline opens up the airways and makes breathing easier. It accomplishes this by:

increasing cyclic AMP (cAMP) levels by inhibiting phosphodiesterase enzymes, especially PDE3 and PDE4.

Unlike theophylline, it has anti-inflammatory qualities without causing a lot of heart stimulation.

enhancing mucociliary clearance and respiratory muscle performance.

Doxofylline is a safer substitute for standard xanthines because it has fewer stimulatory effects on the cardiovascular and central nervous systems, which is especially important for older or heart-problematic individuals.

Indications

Doxofylline 200 mg is frequently administered to treat:

Asthma bronchial

COPD stands for chronic obstructive pulmonary disease.

Emphysema

Additional long-term respiratory conditions that involve bronchospasm

In moderate to severe respiratory disorders, it is usually used as an adjuvant therapy in conjunction with beta-agonists or inhaled corticosteroids.

Dosage and Administration

The age, weight, and severity of the patient’s disease all affect the suggested dosage of 200 mg of. Always abide by the dosage and duration recommendations made by your doctor. The usual dosage for adults is:

200–400 mg, two–three times a day, either before or after meals.

Avoid crushing or chewing the tablet; instead, consume it whole with water. To keep the medication at a steady level in the bloodstream, patients should take it at consistently spaced intervals and avoid skipping doses.

Contraindications

Patients with the following conditions should not take 200 mg of:

Known sensitivity to other xanthine derivatives, such as doxofylline

Extremely low blood pressure

Acute phase myocardial infarction

Peptic ulcer disease

Precautions and Warnings

Before beginning, let your doctor know if you have any of the following conditions:

impairment of the kidneys or liver

Disorders of the heart beat

Disorders of seizures

Breastfeeding or pregnancy

Elderly people and those with a history of drug sensitivity should use this medication with caution. Limiting alcohol and caffeine consumption is advised because they may exacerbate the medication’s negative effects.

Drug Interactions

The following may interact with doxofylline:

Beta-blockers (propranolol, for example)

Antibiotics (such as ciprofloxacin and erythromycin)

Anticonvulsants (such as phenobarbital and phenytoin)

Other stimulants or bronchodilators

To prevent negative interactions, always let your doctor know about all the drugs, vitamins, and herbal products you are using.

Side Effects

Some people may experience side effects from Doxofylline, just like with other drug. Typical adverse effects consist of:

Vomiting or feeling queasy

A headache

Sleeplessness

discomfort in the stomach

mildly elevated heart rate

Serious but uncommon side effects could include:

Reactions to allergies (rash, itching, edema)

An irregular heartbeat or palpitations

seizures (if an overdose occurs)

Get medical help right away if you have any severe or enduring symptoms.

Storage Instructions

Doxofylline 200 mg be kept at room temperature, which is between 20°C and 25°C.

The medication should not be exposed to heat, moisture, or sunlight.

Keep out of children’s and pets’ reach.

Conclusion

Doxofylline 200 mg is an effective and relatively well-tolerated bronchodilator used in the treatment of chronic respiratory disorders such as asthma and COPD. Its improved safety profile over traditional xanthines makes it a preferred choice for many healthcare professionals. As with all medications, it should be used under medical supervision, following the prescribed dosage and instructions.

Always consult your doctor or pharmacist before starting or stopping any medication.

Order Now At Mdx Pharma bd….

To order from MDX Pharma BD, visit their website at https://mdxpharmabd.com, where you can browse products and place orders online. For inquiries or orders via email, contact emedicarepharma@gmail.com. Alternatively, call (+88) 01929123476. Their address is 29, Abdullahpur, Uttara, Dhaka-1230, Bangladesh.

1. What is the purpose of Doxofylline syrup?
Asthma and chronic obstructive pulmonary disease (COPD) are treated with doxolator 100mg syrup, a bronchodilator.

2. Does a cough respond well to doxofylline?
Doxofylline, a methylxanthine derivative, works primarily by inhibiting the phosphodiesterase activity in smooth muscle cells, which relaxes the bronchus’ smooth muscle. Doxofylline can thereby reduce coughing and promote airway ventilation.

3. Is it safe to take doxofylline every day?
Are You Curious? Doxofylline has been prescribed to you in order to prevent and treat chronic obstructive pulmonary disease (COPD) and asthma. It should be taken daily at the same time, ideally right after meals in the evening. It doesn’t act immediately, and it shouldn’t be used to treat acute respiratory issues.

4. Can I take montelukast and doxofylline at the same time?
For the prevention and treatment of asthma, you have been prescribed Doxofylline + Montelukast. It has extremely few adverse effects and is comparatively harmless. Take it every day at the same time, ideally right after dinner.