Cholcut 20 mg (Rosuvastatin)

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Cholcut is indicated in-

  • Heterozygous Hypercholesterolemia (Familial and Non familial)
  • Homozygous Hypercholesterolemia (Familial)
  • Mixed Dyslipidemia (Fredrickson Type IIa and IIb)
  • Primary prevention of cardiovascular disease
Rosuvastatin is a selective and competitive inhibitor of HMG-CoA reductase, the rate-limiting enzyme that converts 3-hydroxy-3-methyl glutaryl coenzyme A to mevalonate, a precursor of cholesterol. Rosuvastatin produces its lipid-modifying effects in two ways. First, it increases the number of hepatic LDL receptors on the cell surface to enhance uptake and catabolism of LDL. Second, Rosuvastatin inhibits hepatic synthesis of VLDL, which reduces the total number of VLDL and LDL particles.
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    Rosuvastatin Calcium, a potent statin mostly used to control cholesterol levels in the body, is an ingredient in the prescription drug Cholcut 20 mg. Rosuvastatin, a member of the statin family, increases “good” cholesterol (HDL) while decreasing “bad” cholesterol (LDL) and triglycerides in the blood. In order to assist avoid heart attacks, strokes, and other dangerous illnesses, people with excessive cholesterol, hyperlipidemia, and other cardiovascular risks are frequently prescribed Cholcut 20 mg.


    Composition

    Each 20 mg Cholcut pill includes:

     

    The calcium equivalent of 20 mg of rosuvastatin

     

    Lactose monohydrate, magnesium stearate, crospovidone, microcrystalline cellulose, and film-coating agents are examples of excipients.

     

    Class of Therapeutics

     

    Cholcut is a member of the class of drugs called statins, which are HMG-CoA reductase inhibitors. These medications function by inhibiting the liver’s enzyme that produces cholesterol.

     


    Medical Uses and Indications

    The following conditions are treated with Cholcut 20 mg:

     

    Primary Hypercholesterolemia: To reduce adults’ excessive levels of ApoB, total cholesterol, and LDL-C.

     

    Managing high triglyceride and cholesterol levels is known as mixed dyslipidemia.

     

    When combined with other lipid-lowering treatments, homozygous familial hypercholesterolemia is utilized.

     

    Preventing cardiovascular disease lowers the risk of heart attacks, strokes, and arterial revascularization in high-risk individuals.

     

    Atherosclerosis: Reduces the rate at which atherosclerosis, or plaque accumulation in the arteries, advances.

     


    How It Works

    The liver’s production of cholesterol depends on the enzyme HMG-CoA reductase, which is inhibited by rosuvastatin in Cholcut 20 mg. The body extracts more LDL cholesterol from the bloodstream when cholesterol production is decreased, hence lowering total LDL levels. It also helps lower triglyceride levels and encourages an increase in HDL (good cholesterol).

     


    Dosage and Administration

    10 mg or 20 mg once daily is the typical starting dose, depending on the patient’s needs and cholesterol levels.

     

    Usually taken once daily, Cholcut 20 mg can be taken with or without meals.

     

    After four weeks, a healthcare professional may modify the dosage in accordance with the lipid response.

     

    Lower starting doses may be necessary for elderly patients, patients with hepatic or renal impairment, and patients taking several drugs at the same time.

     

    Note: Don’t alter the dosage without first consulting your doctor; always do as directed.


    Side Effects

    Although not everyone experiences them, Cholcut 20 mg may have adverse effects like any other medicine. Typical adverse effects consist of:

     

    A headache

     

    Weakness or pains in the muscles

     

    Pain in the abdomen

     

    Feeling queasy

     

    Constipation

     

    Serious adverse effects, however uncommon:

     

    Rhabdomyolysis or myopathy (breakdown of muscles)

     

    Abnormalities of liver enzymes

     

    Reactions to allergies (rash, itching, edema)

     

    Confusion or memory loss (rare cognitive adverse effects)

     

    Get medical help right away if you have discomfort in your muscles or black urine.

     


    Precautions and Warnings

    Before taking 20 mg of Cholcut, let your doctor know if you have:

     

    Liver illness

     

    Kidney issues

     

    An alcohol abuse history

     

    Thyroid conditions

     

    Breastfeeding or pregnancy

     

    Cholcut may be harmful to the fetus or baby, hence it is not advised during pregnancy or when nursing. Women of childbearing age who are taking this medicine should use effective contraception.

     


    Drug Interactions

    20 mg of Cholcut may interact with:

     

    Cyclosporine

     

    Warfarin

     

    Other fibrates, including gemfibrozil

     

    Antacids that contain magnesium or aluminum

     

    HIV is treated with protease inhibitors.

     

    To prevent drug interactions, always provide your doctor a full list of all the medications and supplements you use.

     


    Lifestyle and Dietary Considerations

    Cholcut 20 mg (Rosuvastatin) aids in cholesterol regulation, although it should be used in combination with:

     

    A heart-healthy, low-fat diet

     

    Frequent exercise

     

    Quitting smoking

     

    Controlling weight

     

    Maintaining a healthy lifestyle lowers the risk of cardiovascular problems and increases the effectiveness of Cholcut.

     


    Storage Instructions

    • Store at room temperature (15°C to 30°C).
    • To keep the drug safe from light and moisture, keep it in its original container.Keep out of reach of children.

    Conclusion

    A clinically validated drug for controlling high cholesterol and lowering cardiovascular risks is Cholcut 20 mg (rosuvastatin). It can dramatically reduce your risk of heart disease and serious cardiovascular events when taken as directed and combined with a healthy lifestyle. Like all statins, though, it needs to be properly monitored by a doctor because of possible interactions and side effects. For treatment to be safe and effective, regular cholesterol monitoring and communication with your healthcare practitioner are crucial.


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    To order from MDX Pharma BD, visit their website at https://mdxpharmabd.com, where you can browse products and place orders online. For inquiries or orders via email, contact emedicarepharma@gmail.com. Alternatively, call (+88) 01929123476. Their address is 29, Abdullahpur, Uttara, Dhaka-1230, Bangladesh.

     

    1. What is the purpose of 20 mg of rosuvastatin?
    Description: Rosuvastatin is used in conjunction with a healthy diet to raise your HDL and decrease your LDL and triglycerides (fats) in the blood. Adults who are unable to regulate their cholesterol levels with diet and exercise alone are also treated with it.

     

    2. How long does 20 mg of rosuvastatin take to start working?
    Although rosuvastatin begins lowering cholesterol within a week, it may take up to a month for its full effects to manifest. If you take your medication as directed on a regular basis, your cholesterol levels should decrease in four weeks. Do side effects persist over time? Long-term use of rosuvastatin is safe.

     

    3. Which rosuvastatin side effect is the most dangerous?
    Less than 1 in 1,000 persons experience serious adverse effects. If you get unexplained muscle discomfort, sensitivity, weakness, or cramps—all of which could indicate kidney damage and muscle breakdown—stop taking rosuvastatin and contact a doctor or 111 right away.

     

    4. When is the ideal time to take 20 mg of rosuvastatin?
    Rosuvastatin is typically taken once daily. Although you can take it whenever you want, it is better to take it daily at the same time. You can take rosuvastatin with or without food because it normally doesn’t cause stomach problems. With a glass of water, swallow the rosuvastatin tablets whole.

    Generic Name:

    Rosuvastatin

    Theraputic Category:

    Lipid Lowering Agent

    Pack Size:

    (5 mg : 3 x 10's), (10mg : 2×10's), (20mg : 2×10's)