Bilargo 20 mg is primarily used to treat allergic illnesses such as hay fever (allergic rhinitis), urticaria (hives), and other allergic skin reactions. Bilargo’s active ingredient is bilastine, a second-generation antihistamine known for its long-lasting effects and lack of sedative properties.

Composition and Formulation

Bilastine 20 mg is the active component in Bilargo 20 mg. It is intended for oral administration and comes in tablet form. Typically, the tablets are spherical, film-coated, and white or off-white to facilitate swallowing. Microcrystalline cellulose, magnesium stearate, croscarmellose sodium, and silica colloidal anhydrous are examples of inactive substances.

Pharmacodynamics and Mechanism of Action

Bilargo 20 mg contains the selective H1-receptor antagonist bilastine as its active ingredient. Histamine is a substance that the immune system releases during allergic reactions, and it functions by preventing its effects. Bilastine does not readily penetrate the blood-brain barrier like first-generation antihistamines do, which lessens the possibility of sleepiness or sedation.

Indications and Uses

Bilargo 20 mg is prescribed for the relief of symptoms associated with:

Allergic Rhinitis:  Sneezing, runny nose, nasal congestion, and watery or itchy eyes brought on by seasonal or persistent allergies are all efficiently reduced by it.

Chronic Idiopathic Urticaria: It alleviates itching, redness, and swelling associated with chronic hives.

Other Allergic Conditions: Bilargo is sometimes used in cases of skin allergies, insect bites, and mild food allergies.

Dosage and Administration

Adults and adolescents (those over 12): One tablet (20 mg) once daily is the suggested dosage.

Food can lessen its effectiveness, therefore it is best to take it empty-handed, at least an hour before or two hours after a meal.

With a glass of water, swallow the tablet whole.

Pharmacokinetics

Absorption: When taken orally, bilastine is quickly absorbed and reaches its maximal plasma concentration in one to one and a half hours.

Metabolism: It has a low liver metabolism, which lowers the possibility of medication interactions.

Elimination: Bilastine has a half-life of roughly 14 to 16 hours and is mostly eliminated unaltered in urine and feces.

Contraindications

Bilargo 20 mg should not be used in individuals who:

Have a known hypersensitivity to Bilastine or any excipient in the formulation.

Are below 12 years of age (unless prescribed by a doctor).

Warnings and Precautions

Kidney Impairment: Patients with severe renal impairment should use Bilargo cautiously, as it is primarily eliminated via the kidneys.

Liver Impairment: No dosage adjustment is required, but it is advisable to consult a doctor before use.

Pregnancy and Breastfeeding: Bilargo should only be used if necessary and prescribed by a doctor, as limited data is available regarding its safety during pregnancy and lactation.

Alcohol and CNS Depressants: While Bilargo is non-sedative, alcohol or other CNS depressants may enhance drowsiness in some individuals.

Side Effects

Although bilargo 20 mg is usually well tolerated, some people may have minor adverse effects like:

Headache, lightheadedness, dry mouth, exhaustion, and nausea are typical adverse effects.

Skin rashes, elevated heart rate, and abdominal pain are uncommon side effects.

Rare but serious allergic reactions include breathing difficulties and facial or throat swelling, which call for emergency medical care.

Drug Interactions

Some compounds may interact with bilargo, such as:

Grapefruit juice: May lessen the way the medication is absorbed.

Diltiazem, ketoconazole, and erythromycin: May raise blood levels of bilastine.

Rifampicin: May lower blood levels of the protein bilastine.

Antacids: To prevent decreased absorption, they should be taken at least two hours apart from bilargo.

Storage Instructions

Store at room temperature (15-30°C), away from moisture and direct sunlight.

Keep out of reach of children.

Do not use beyond the expiration date mentioned on the packaging.

Conclusion

Bilargo 20 mg (Bilastine) is a potent, non-sedative antihistamine that relieves urticaria and allergic rhinitis. For those looking for long-term allergy treatment without experiencing severe sleepiness, it is the recommended option due to its positive safety profile and low frequency of drug interactions. However, it should only be taken under a doctor’s supervision, especially if the patient has renal impairment, is pregnant, or is on other medications.

Order Now At Mdx Pharma bd….

To order from MDX Pharma BD, visit their website at https://mdxpharmabd.com, where you can browse products and place orders online. For inquiries or orders via email, contact emedicarepharma@gmail.com. Alternatively, call (+88) 01929123476. Their address is 29, Abdullahpur, Uttara, Dhaka-1230, Bangladesh.

Q. Can kidneys safely use bilastine?
Elderly patients and those with hepatic or renal impairment do not need to change their dosage. Generally speaking, bilastine is well tolerated, even at higher dosages.

Q. What kind of tablet is bad for the kidneys?
Popular cold and pain remedies, known as NSAIDs, might harm your kidneys if taken for an extended period of time or cause acute renal injury if taken while dehydrated or with low blood pressure.