Indication:
Barigen capsules, containing 4 mg of Baricitinib, are prescribed for treating inflammatory conditions like rheumatoid arthritis and dermatological disorders such as atopic dermatitis.

Pharmacology:
Baricitinib, a Janus kinase (JAK) inhibitor, operates by suppressing specific enzymes involved in inflammation. It targets JAK1 and JAK2 enzymes, crucial in signaling pathways regulating immune responses. This inhibition aids in diminishing inflammation and relieving symptoms associated with rheumatoid arthritis and atopic dermatitis.

Dosage and Administration:
Typically, Barigen capsules are taken orally once daily. The dosage varies based on the condition being treated, patient response, and individual factors. Adhering to the dosage instructions provided by the healthcare provider is essential.

Interaction:
Baricitinib may interact with certain medications, including immunosuppressants and biologic agents used in autoimmune disease treatment. Patients should inform their healthcare provider about all medications, supplements, and herbal products they are using to avoid potential interactions.

Side Effects:
Common side effects of Barigen capsules may include headache, upper respiratory tract infections, nausea, and diarrhea. More severe side effects like increased infection risk, liver enzyme elevations, and thrombosis may occur. Patients should promptly seek medical attention for severe or persistent side effects.

Precautions and Warnings:
Patients on Barigen capsules should be monitored for signs of infection, liver function abnormalities, and blood clotting disorders. Baricitinib may heighten infection risk and should be cautiously used in patients with a history of chronic or recurrent infections. Discussing the treatment’s risks and benefits with the healthcare provider is crucial.

Overdose Effects:
In cases of Barigen capsule overdose, patients may experience intensified adverse effects like increased infection risk and elevated liver enzymes. Management usually involves supportive care and monitoring for complications. Immediate medical attention is recommended if overdose is suspected.