Cefixime 400 mg, a third-generation cephalosporin antibiotic used to treat a range of bacterial infections, is marketed under the name Fixacef. Because it stops bacteria from growing, it works against a wide variety of gram-positive and gram-negative species. Cefixime is frequently prescribed for ear, urinary, and respiratory infections due to its broad-spectrum antibiotic action and ease of oral administration.

Composition and Formulation:

Every Fixacef tablet includes:

400 mg of cefixime (as cefixime trihydrate) is the active component.

Form of dosage: oral tablet

Administration method: oral

Usually sold in blister packets, Fixacef should be kept out of direct sunlight and in a cool, dry location.

Cefixime’s mode of action involves preventing the formation of bacterial cell walls. Similar to other β-lactam antibiotics, it attaches itself to penicillin-binding proteins (PBPs) within the bacterial cell wall, causing structural disruption and ultimately cell death and lysis. This bactericidal activity works well on a variety of vulnerable organisms.

Indications and Uses:

The following infections are frequently treated with Fixacef (Cefixime 400 mg):

infections of the upper respiratory tract, such as sinusitis, pharyngitis, and tonsillitis.

infections of the lower respiratory tract, including mild-to-moderate pneumonia and bronchitis.

urinary tract infections (UTIs), which include simple pyelonephritis and cystitis.

Ear infections, particularly acute otitis media.

STIs, such simple gonorrhea, are sexually transmitted infections.

In certain situations, typhoid fever may be used as an alternate treatment.

Cefixime is ineffective against viral illnesses such as the common cold or influenza.

Dosage and Administration:

Cefixime’s usual dosage for adults is:

200 mg every 12 hours or 400 mg once day, depending on the doctor’s instructions.

The dosage may be changed for kids and teenagers dependent on their age and weight.

Depending on the nature and severity of the illness, treatment typically lasts anywhere from five to fourteen days.

It is recommended that tablets be taken whole, with or without meal, and with water. It may lessen stomach pain if taken with food.

Note: Even if symptoms subside early, always take the medication as directed and finish the entire course.

Contraindications:

Cefixime 400 mg (Fixacef) should not be used by anyone who have:

a recognized allergy or hypersensitivity to cefixime or other medicines that are cephalosporins.

a history of severe penicillin antibiotic allergic reactions (perhaps owing to cross-reactivity).

Warnings and Precautions:
Renal impairment: Patients with severe renal dysfunction may require dose adjustments.

Use during pregnancy and lactation should be determined by a healthcare provider’s risk-benefit analysis.

Superinfections: Extended use may lead to fungal overgrowth and other secondary infections.

Antibiotic resistance: Overuse or unnecessary use of antibiotics might result in reduced efficacy.

Before beginning Fixacef, always let your doctor know about any past medical conditions or current drugs.

Side Effects:

Although not everyone has them, Fixacef may have adverse effects like any other medicine. Typical adverse effects consist of:

Having diarrhea

Feeling queasy

Pain in the abdomen

A headache

Rashes on the skin

Serious but less frequent side effects include:

extreme allergic responses, such as anaphylaxis

Blood conditions (such as leukopenia and thrombocytopenia)

Increases in liver enzymes

Diarrhea linked to Clostridium difficile (CDAD)

Any severe or unusual reactions should be immediately reported to your healthcare provider.

Drug Interactions:

The following may interact with Fixacef:

Warfarin is one example of an anticoagulant that may raise the risk of bleeding.

Elevated blood levels of carbamazepine may result.

By decreasing its excretion, probenecid may raise cefixime levels.

To prevent drug interactions, always include a complete list of all currently prescribed medications.

Storage Guidelines:

Keep at or below 25°C (77°F).

Keep out moisture and light by storing it in its original container.

Keep out of children’s reach.

Conclusion:

A dependable, broad-spectrum antibiotic, cefixime 400 mg (Fixacef) is used to treat a range of bacterial infections. It is a recommended choice for outpatient treatments because to its once-daily dosage and potent action against both gram-positive and gram-negative germs. To preserve its efficacy and reduce the possibility of resistance, however, prudent use is essential. Fixacef should always be taken under the supervision of a licensed healthcare provider.

Order Now At Mdx Pharma bd….

To order from MDX Pharma BD, visit their website at https://mdxpharmabd.com, where you can browse products and place orders online. For inquiries or orders via email, contact emedicarepharma@gmail.com. Alternatively, call (+88) 01929123476. Their address is 29, Abdullahpur, Uttara, Dhaka-1230, Bangladesh.

1. What is the purpose of Cefixime 400 mg (Fixacef)?
The antibiotic cefixime is used to treat a number of bacterial illnesses, such as tonsillitis, sinusitis, respiratory tract infections (such as bronchitis), gonorrhea, and urinary tract infections.

2. How should 400 mg of Fixacef be taken?
Fixacef should be taken exactly as prescribed by your doctor, usually once day, with or without meals. Using water, swallow the tablet whole.

3. Can I take Fixacef without eating?
Fixacef can be taken either way, though taking it with food may help lessen stomach discomfort.

4. What is the duration of action for Cefixime?
In order to prevent resistance and relapse, it’s crucial to finish the entire course of antibiotics, even though you could feel better in one to three days.

5. What are Fixacef 400 mg’s typical adverse effects?
The following are typical adverse effects: headache, indigestion, diarrhea, nausea, and abdominal pain. Speak with your physician if it’s severe or ongoing.

6. For whom is Fixacef inappropriate?
Cefixime should be avoided by those who are known to be allergic to cephalosporin antibiotics. Never keep your allergy history a secret from your physician.