Olanib(Olaparib INN) 50 mg
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Olanib, containing Olaparib as its active ingredient with the International Nonproprietary Name (INN), is primarily used to treat ovarian, breast, and pancreatic cancers. Acting as a poly (ADP-ribose) polymerase (PARP) inhibitor, Olanib disrupts cancer cell DNA repair processes, leading to their demise. The standard dosage regimen involves taking 50 mg of Olanib orally twice daily, typically with or without food. Potential side effects, including nausea, vomiting, fatigue, anemia, and diarrhea, necessitate vigilant monitoring and regular medical supervision throughout the course of treatment.
Indications: Olaparib is prescribed for several cancer types, including ovarian, breast, and pancreatic cancers, under specific conditions such as recurrence or mutations like BRCA mutations.
Pharmacology: Olaparib operates by hindering PARP enzymes, pivotal in cell DNA repair. This inhibition impairs cancer cells’ ability to mend their DNA, resulting in cell death.
Dosage and Administration: Typically, Olaparib is taken orally in 300 mg doses twice daily, with or without food. Adjustments might be necessary based on individual patient responses and side effects.
Interactions: Olaparib can interact with various medications, necessitating patients to disclose their entire medication list to healthcare providers, including prescriptions, over-the-counter drugs, supplements, and vitamins.
Side Effects: Common side effects encompass nausea, vomiting, fatigue, anemia, reduced appetite, diarrhea, and abdominal discomfort. Serious effects may include bone marrow suppression and heightened risk of specific cancers.
Precautions and Warnings: Olaparib usage may result in bone marrow suppression, prompting regular blood tests for monitoring blood cell counts. Additionally, patients should be monitored for potential new cancer developments.
Overdose Effects: In instances of overdose, supportive measures are employed as there’s no specific antidote. Treatment focuses on alleviating symptoms and providing supportive care.
Product Name | Olanib |
---|---|
Generic Name | Olaparib INN |
Formulation | Capsule |
Available Pack size | 112 Capsules |
Strengths | 50 mg |
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